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IV Therapy in Denver, CO

Recharge and rehydrate at our South Pearl Street lounge in the heart of Platt Park. Walk-ins welcome.
★★★★★ 405+ Google Reviews
Address

1490 S Pearl St #100
Denver, CO 80210

Phone

(720) 883-1665
Call or Text

Hours

Mon-Fri: 10am - 6pm
Saturday: 10am - 4pm
Sunday: 9am - 1pm

Welcome to Twin Rivers IV Denver

Located on historic South Pearl Street in Denver’s beloved Platt Park neighborhood, our Denver lounge offers a relaxing retreat for IV therapy, vitamin infusions, and wellness treatments. Whether you’re recovering from a big weekend, training for your next race, battling Denver’s dry climate, or simply looking to boost your energy, our experienced nursing team is here to help.

We opened our doors on South Pearl Street in 2019 as the second Twin Rivers location, following the success of our original Littleton lounge. Since then, we’ve become a neighborhood staple—just steps from the Sunday Farmers’ Market and surrounded by the tree-lined streets, boutique shops, and local restaurants that make Platt Park one of Denver’s most walkable neighborhoods.

We’re easily accessible from Washington Park, Baker, and the greater South Denver area. Street parking is available on Pearl Street, plus we have a private lot behind the building.

Our Services in Denver

At Twin Rivers IV Denver, we offer a full range of IV therapy and wellness services administered by experienced registered nurses. Whether you’re seeking rapid hydration, immune support, athletic recovery, or anti-aging treatments, we’ll help you find the right solution for your wellness goals.

Our IV blends deliver hydration, vitamins and nutrients directly to your bloodstream. Choose a Health & Wellness IV, an Essential Blend like the Myers’ or Athletic, a Signature Blend like Travel Support or Hangover Recovery, or one of our Specialty Immunity Blends. Elite Wellness members get two blends a month.

Quick vitamin shots for those on the go. B-12 for energy, Vitamin D for immunity, Glutathione for detox and skin health, and more. Same 100% absorption as IV therapy, but faster—perfect for busy schedules.

Nicotinamide Adenine Dinucleotide (NAD+) supports cellular energy production, DNA repair, and healthy aging. Available in multiple dosages via infusion or injection. Popular for mental clarity, anti-aging, and recovery support.

Targeted peptide treatments for weight management, muscle recovery, immune support, and anti-aging. Our medical team will help you determine the right protocol for your goals.

Medically supervised weight loss programs with one monthly price. Every month includes a weekly medication injection, a weekly LipoStat injection and provider supervision throughout. Programs begin with an enrollment visit that covers your consultation and labs.

Get insights into your health with wellness lab testing. Identify nutrient deficiencies, hormonal imbalances, and other markers to create a personalized wellness plan.

Elite Wellness ($199 a month): 2 blended IVs, 2 vitamin injections, a birthday infusion, a quarterly bring-a-friend pass, approx. 25% off everything, River Rewards and priority booking. Base Wellness ($149 a month): 2 Health & Wellness IVs and 2 B-12 injections. Express Wellness ($99 a month): one vitamin injection weekly. Month to month, no minimum term.

Ready to Feel Your Best?

Book online or walk in today — no appointment needed.

Meet Your Denver Team

Alyssa Kitting, RN, BSN

Lounge Manager

Alyssa pairs high-acuity Labor & Delivery experience with a wellness-first approach to IV infusion therapy. A DAISY Award–winning nurse with her BSN, she’s Colorado-licensed and certified in BLS, ACLS, NRP, and C-EFM.

At Swedish Medical Center in Denver, Alyssa is known for establishing IV access quickly and comfortably while managing hydration and medication protocols with precision and a gentle, confident touch. Her background includes continuous bedside care for laboring, antepartum, postpartum, and surgical OB patients; real-time interpretation of maternal/fetal monitoring; and safe titration of high-alert medications.

Rooted in holistic, preventive wellness, Alyssa creates a supportive environment where clients feel seen, informed, and empowered. She brings the same standard of aseptic technique, patient advocacy, and clinical judgment to every IV—so you leave feeling better, cared for, and confident in your health journey.

Why Choose Twin Rivers Denver

Experienced RN Staff

Every IV is administered by a registered nurse with at least 5 years of clinical experience. No techs, no shortcuts.

Colorado-Born & Locally Owned

Founded in Colorado in 2018 and still run by our founder, who works in the lounges.

Relaxing Lounge Environment

Our Denver lounge is designed for comfort. Sink into a cozy chair, enjoy refreshments, and let us take care of you.

Walk-Ins Welcome

No appointment needed for most services. Stop by when it's convenient for you.

Membership Savings

Elite Wellness members save approx. 25% on everything. Memberships start at $99 a month.

What Our Denver Clients Say

★★★★★ 5.0 Rating
405+ Google Reviews

Visit Our Denver Lounge

Twin Rivers IV & Wellness Lounge
Address

1490 S Pearl St #100
Denver, CO 80210

Phone

(720) 883-1665
Call or Text

Hours

Mon-Fri: 10am - 6pm
Saturday: 10am - 4pm
Sunday: 9am - 1pm

Parking

Free street parking, plus paid parking garage 3 buildings south on Pearl St.

Getting Here:

From I-25: Take the Broadway exit, head south on Broadway, turn left (east) on Louisiana Ave, then right (south) on S Pearl St. We’re located on the NE corner of Florida Ave and Pearl St, in the heart of Platt Park.

Denver Location FAQs

Where is Twin Rivers IV located in Denver?

We’re located at 1490 S Pearl Street in Denver’s Platt Park neighborhood, on historic South Pearl Street on the NE corner of Florida Ave and Pearl St. Free street parking is available, plus a paid garage a few doors south of the lounge.  We’re just steps from the Sunday Farmers’ Market and an easy walk from Washington Park.

Walk-ins are welcome! Come in when it’s convenient for you. If you prefer to book in advance or want to guarantee a specific time (especially on busy weekends), you can book online through our website.
Absolutely. IV hydration is one of the fastest ways to combat altitude sickness symptoms. Denver’s mile-high elevation can cause dehydration, headaches, fatigue, and nausea—especially for visitors. Our Travel Support Blend delivers fluids, vitamin C, zinc and magnesium directly to your bloodstream to help you acclimate faster and feel your best.
At your first appointment, we’ll take a few extra minutes to get to know you and ensure your safety. We’ll discuss your wellness goals, review your medical history, take your vitals, and have you complete a brief waiver. Most IV therapy sessions take about 30 minutes—for your first visit, please plan for an additional 15 minutes for the intake process.
Registered nurses! At Twin Rivers, we hire highly trained and skilled registered nurses to educate and help you choose the service that’s right for you. Each of our staff members has no less than five years of clinical experience and will spend the necessary time with each client to make your visit unique to you.
We don’t accept insurance directly; however, clients have been able to use their HSA cards and MediFlex plans to cover the services we offer.

Monday through Friday 10am-6pm, Saturday 10am-4pm, and Sunday 9am-1pm. During Farmers’ Market season (May through November), we have special extended Sunday hours to accommodate the market crowd.

Book a Free Nursing Consult

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Not Sure Where to Start? Let Us Help.

Our nursing team will help you find the perfect wellness plan for YOUR goals.
Start with a free RN consult:

RN Consult

FREE

15 minutes

A quick Q&A to answer your questions and point you in the right direction.

Ready to Feel Your Best?

Book online or walk in today. We're here to help.

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