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IV Therapy in Denver, CO

Recharge and rehydrate at our South Pearl Street lounge in the heart of Platt Park.

★★★★★ 405+ Google Reviews

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What to Expect...

Step 1
Book a Time

Mention SPECIAL CODE: AD2604
for the new client special

Step 2
Relax in Comfort

Enjoy our comfortable chairs, snacks, and great company during your visit

Step 3
Feel Great

Leave feeling better, more energetic, and healthier.

Our Services in Denver

At Twin Rivers IV Denver, we offer a full range of IV therapy, wellness, and weight-loss services, administered by experienced registered nurses. Whether you’re seeking rapid hydration, immune support, athletic recovery, biohacking, or anti-aging treatments, we’ll help you find the right solution for your wellness goals.

IV Therapy & Vitamin Boosts

Our signature IV infusions deliver hydration, vitamins, and nutrients directly to your bloodstream for 100% absorption. Choose from our Health & Wellness IV, Immunity Boost, Athletic Recovery, Hangover Cure, and more.

Wellness Injections

Quick vitamin shots for those on the go. B-12 for energy, Vitamin D for immunity, Glutathione for detox and skin health, and more. Same 100% absorption as IV therapy, but faster—perfect for busy schedules.

NAD+ Therapy

Nicotinamide Adenine Dinucleotide (NAD+) supports cellular energy production, DNA repair, and healthy aging. Available in multiple dosages via infusion or injection. Popular for mental clarity, anti-aging, and recovery support.

Peptide Therapy

Targeted peptide treatments for weight management, muscle recovery, immune support, and anti-aging. Our medical team will help you determine the right protocol for your goals.

Medical Weight Loss

Comprehensive weight loss programs and medically-supervised treatments. Includes ongoing support, monitoring, and adjustments to help you reach your goals safely.

Comprehensive Labs

Get insights into your health with comprehensive lab testing. Identify nutrient deficiencies, hormonal imbalances, and other markers to create a personalized wellness plan.

Ready to Feel Your Best?

Book online or walk in today — no appointment needed.

Claim Your SPECIAL DISCOUNT with code: AD2604

Welcome to Twin Rivers IV Denver

Located on historic South Pearl Street in Denver’s beloved Platt Park neighborhood, our Denver lounge offers a relaxing retreat for IV therapy, vitamin infusions, and wellness treatments. Whether you’re recovering from a big weekend, training for your next race, battling Denver’s dry climate, or simply looking to boost your energy, our experienced nursing team is here to help.

We opened our doors on South Pearl Street in 2019 as the second Twin Rivers location, following the success of our original Littleton lounge. Since then, we’ve become a neighborhood staple—just steps from the Sunday Farmers’ Market and surrounded by the tree-lined streets, boutique shops, and local restaurants that make Platt Park one of Denver’s most walkable neighborhoods.

We’re easily accessible from Washington Park, Baker, and the greater South Denver area. Street parking is available on Pearl Street, plus we have a private lot behind the building.

Can’t come to us? Our fully-equipped Airstream mobile lounge brings IV therapy directly to you anywhere in the Denver metro area.

Meet Your Denver Team

Alyssa Kitting, RN, BSN

Lounge Manager

Alyssa pairs high-acuity Labor & Delivery experience with a wellness-first approach to IV infusion therapy. A DAISY Award–winning nurse with her BSN, she’s Colorado-licensed and certified in BLS, ACLS, NRP, and C-EFM.

At Swedish Medical Center in Denver, Alyssa is known for establishing IV access quickly and comfortably while managing hydration and medication protocols with precision and a gentle, confident touch. Her background includes continuous bedside care for laboring, antepartum, postpartum, and surgical OB patients; real-time interpretation of maternal/fetal monitoring; and safe titration of high-alert medications.

Rooted in holistic, preventive wellness, Alyssa creates a supportive environment where clients feel seen, informed, and empowered. She brings the same standard of aseptic technique, patient advocacy, and clinical judgment to every IV—so you leave feeling better, cared for, and confident in your health journey.

Why Choose Twin Rivers Denver

Experienced RN Staff

Every IV is administered by a registered nurse with at least 5 years of clinical experience. No techs, no shortcuts.

Colorado-Born & Locally Owned

Founded in Colorado in 2018, Twin Rivers is a local business—not a franchise. Our founder still works in the lounges.

Relaxing Lounge Environment

Our Denver lounge is designed for comfort. Sink into a cozy chair, enjoy refreshments, and let us take care of you.

Mobile Services Available

Our vintage Airstream brings the lounge experience to you—at home, at work, or at your event anywhere in Denver.

Walk-Ins Welcome

No appointment needed for most services. Stop by when it's convenient for you.

Membership Savings

Members save at least 50% on IV therapy, health, wellness, and weight loss plans.

What Our Denver Clients Say

★★★★★
Clients Love Us!

Visit Our Denver Lounge

Twin Rivers IV & Wellness Lounge
Address

1562 S Pearl St
Denver, CO 80210

Phone

(720) 883-1665
Call Today!

Hours

Mon-Fri: 10am - 6pm
Saturday: 10am - 4pm
Sunday: 9am - 1pm

Parking

Street parking on
S Pearl St. Private lot behind building (enter from alley).

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Denver Location FAQs

Where is Twin Rivers IV located in Denver?
We’re located at 1562 S Pearl Street in Denver’s Platt Park neighborhood, on historic South Pearl Street between Iowa and Arkansas Streets. Street parking is available on Pearl Street, plus we have a private parking lot behind the building (accessible from the alley). We’re just steps from the Sunday Farmers’ Market and an easy walk from Washington Park.
Walk-ins are welcome! Come in when it’s convenient for you. If you prefer to book in advance or want to guarantee a specific time (especially on busy weekends), you can book online through our website.
Yes! We offer mobile IV services throughout the Denver metro area with our fully-equipped vintage Airstream. We service individuals at home, groups of friends, bachelor/bachelorette parties, corporate wellness events, sporting events, and more. There’s a $100 service fee for groups under 6 people (waived for groups of 6+). Call us at (720) 883-1665 to schedule.
Absolutely. IV hydration is one of the fastest ways to combat altitude sickness symptoms. Denver’s mile-high elevation can cause dehydration, headaches, fatigue, and nausea—especially for visitors. Our Rehydrate IV delivers fluids, electrolytes, and vitamins directly to your bloodstream to help you acclimate faster and feel your best.
At your first appointment, we’ll take a few extra minutes to get to know you and ensure your safety. We’ll discuss your wellness goals, review your medical history, take your vitals, and have you complete a brief waiver. Most IV therapy sessions take about 30 minutes—for your first visit, please plan for an additional 15 minutes for the intake process.
Registered nurses! At Twin Rivers, we hire highly trained and skilled registered nurses to educate and help you choose the service that’s right for you. Each of our staff members has no less than five years of clinical experience and will spend the necessary time with each client to make your visit unique to you.
We don’t accept insurance directly; however, clients have been able to use their HSA cards and MediFlex plans to cover the services we offer.

Monday through Friday 10am-6pm, Saturday 10am-4pm, and Sunday 9am-1pm. During Farmers’ Market season (May through November), we have special extended Sunday hours to accommodate the market crowd.

Ready to Feel Your Best?

Book online or walk in today. We're here to help.

Claim Your SPECIAL DISCOUNT with code: AD2604

Copyright © 2026 Twin Rivers IV & Wellness Lounge. All Rights Reserved.

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