First Time? Come In For a FREE Consult

IV Therapy in Clayton, NC

Recharge and rehydrate at our Clayton lounge in Flowers Plantation, just 25 minutes from Raleigh. Walk-ins welcome.

★★★★★ 5-Star Rated on Google
Address

4879 NC HWY 42 E, Suite G
Clayton, NC 27527

Phone

(919) 631-6574
Call or Text

Hours

Tue, Wed, Thu - 10am - 4pm
Fri - 11am-5pm
Sat - 10am-4pm
Sun - Closed

Welcome to Twin Rivers IV Clayton

Located in the heart of Flowers Plantation—the largest planned community in North Carolina’s Research Triangle—Twin Rivers IV Clayton brings world-class IV therapy and wellness services to Johnston County. We’re just 25 minutes from downtown Raleigh and 10 minutes from downtown Clayton.

Our Clayton lounge offers a full range of services including IV therapy, wellness injections, NAD+ treatments, infrared sauna sessions, medically guided weight loss, and comprehensive lab testing. Whether you’re a busy professional commuting to RTP, a Flowers Plantation resident, or anyone seeking better energy and wellness, our experienced team is here to help.

What makes our Clayton location special is the deep personal care our owner Sara brings to every client interaction. From former ER nursing to proactive wellness, our mission is to help you feel better, live longer, and truly be seen.

We also have a second North Carolina location in Goldsboro—just 30 minutes east!

Our Services in Clayton

At Twin Rivers IV Clayton, we offer a comprehensive range of IV therapy and wellness services administered by experienced registered nurses. From rapid hydration and immune support to infrared sauna sessions and medically guided weight loss, we’ll help you find the right treatment for your wellness goals.

Our signature IV infusions deliver hydration, vitamins, and nutrients directly to your bloodstream for 100% absorption. Choose from our Health & Wellness IV, Immunity Boost, Athletic Recovery, Hangover Cure, and more. First-time special: $79 (regularly $135).

Quick vitamin shots for those on the go. B-12 for energy, Vitamin D for immunity, Glutathione for detox and skin health, and more. Same 100% absorption as IV therapy, but faster—perfect for busy schedules.

Nicotinamide Adenine Dinucleotide (NAD+) supports cellular energy production, DNA repair, and healthy aging. Available in multiple dosages via infusion or injection. Popular for mental clarity, anti-aging, and recovery support.

Targeted peptide treatments for weight management, muscle recovery, immune support, and anti-aging. Our medical team will help you determine the right protocol for your goals.

★ AVAILABLE AT CLAYTON
Relax and detox with our full-spectrum infrared sauna. Benefits include improved circulation, muscle recovery, skin purification, stress relief, and calorie burn. Perfect before or after your IV treatment.
Comprehensive weight loss programs including Semaglutide and other medically-supervised treatments. Includes ongoing support, monitoring, and adjustments to help you reach your goals safely.
Get insights into your health with comprehensive lab testing. Identify nutrient deficiencies, hormonal imbalances, and other markers to create a personalized wellness plan.

Save approximately 50% on IV therapy with our monthly membership plans. Elite Membership ($150/mo): 2 Health & Wellness IVs + 2 B-12 injections. Elite+ Membership ($200/mo): 2 Health & Wellness IVs + 2 Boosts + 2 B-12 injections.

Ready to Feel Your Best?

Book online or walk in today — no appointment needed.

Meet Your Clayton Team

Sara Lacombe

Owner & Operator, Lounge Manager

After losing her son in 2022 and being forced to work the day he passed, Sara realized she needed to create a life that allowed her to prioritize what matters most—her family, her freedom, and her purpose. That moment sparked the vision for her wellness lounge: a space she could call her own, where her kids could come to work with her, and where she could control both her time and her income.

Starting in a 150-square-foot room, she poured her heart into building something bigger—moving into a beautiful space in Clayton that quickly took off. When her daughter was diagnosed with cancer, her team rallied, and her business not only survived, it thrived. With her daughter now in remission, Sara celebrated a full-circle moment by opening her second location in Goldsboro exactly one year to the day after she opened Clayton.

Known for her deep empathy and personal connection with clients, Sara brings a rare kind of care to her work—listening closely, tailoring every service to each individual, and treating every person like family. From former ER work to proactive health solutions, her mission is to help people feel better, live longer, and be seen. Her clients often become friends, showing up for birthdays, grand openings, and every meaningful moment in between.

Why Choose Twin Rivers Clayton

Personal Care

Sara and her team treat every client like family. Expect deep empathy, personalized attention, and a genuine connection at every visit.

Experienced RN Staff

Every IV is administered by a registered nurse with clinical experience. From ER backgrounds to proactive wellness—you're in expert hands.

Flowers Plantation

Located in the heart of the Triangle's largest planned community. Just 25 min from Raleigh, 10 min from downtown Clayton.

Infrared Sauna

One of the few Twin Rivers locations offering infrared sauna. Detox, relax, and recover—perfect alongside your IV treatment.

Walk-Ins Welcome

No appointment needed for most services. Stop by when it's convenient for you.

Cozy Atmosphere

A beautiful, calming space where you'll feel like a million bucks. Relaxed vibes, friendly staff, real results.

What Our Clayton Clients Say

★★★★★ 5.0 Rating
80+ Google Reviews

Visit Our Clayton Lounge

Twin Rivers IV & Wellness Lounge
Address

4879 NC HWY 42 E, Suite G Clayton, NC 27527

Phone

(919) 631-6574
Call or Text

Hours

Tue, Wed, Thu - 10am - 4pm
Fri - 11am-5pm
Sat - 10am-4pm
Sun - Closed

LOCATION

In Flowers Plantation, off NC Highway 42 East. Part of the Flowers Crossroads commercial area.

Getting Here:

We’re located in Flowers Plantation—the largest planned community in the Research Triangle area. From Raleigh, take I-40 to US-70 Business East toward Clayton, then turn left on NC-42 East. The lounge is in the Flowers Crossroads commercial area, with plenty of free parking.

  • 25 minutes from downtown Raleigh
  • 10 minutes from downtown Clayton
  • 40 minutes from RDU Airport
  • 45 minutes from Research Triangle Park (RTP)

Also Serving: Goldsboro, NC!

Visit our second North Carolina location, just 30 minutes east of Clayton

Clayton Location FAQs

Where is Twin Rivers IV located in Clayton?

We’re located at 4879 NC Highway 42 East, Suite G, in the Flowers Plantation community. We’re in the Flowers Crossroads commercial area, about 25 minutes from downtown Raleigh and 10 minutes from downtown Clayton.

Our hours vary weekly based on demand and staffing. Please check our Facebook page for the most current schedule, or call/text us at (919) 631-6574.

Walk-ins are welcome! Come in when it’s convenient for you. If you prefer to book in advance or want to guarantee a specific time, you can book online through our website or call (919) 631-6574.

Yes! Our Clayton location offers full-spectrum infrared sauna sessions. It’s a great complement to IV therapy for detox, relaxation, and recovery.

At your first appointment, we’ll take a few extra minutes to get to know you and ensure your safety. We’ll discuss your wellness goals, review your medical history, take your vitals, and have you complete a brief waiver. Most IV therapy sessions take about 30 minutes—for your first visit, please plan for an additional 15 minutes for the intake process.

Registered nurses! At Twin Rivers Clayton, we hire experienced registered nurses—many with ER backgrounds—to educate and help you choose the service that’s right for you.

We don’t accept insurance directly; however, clients have been able to use their HSA cards and MediFlex plans to cover the services we offer.

Yes! We also have a location in Goldsboro, NC—about 30 minutes east of Clayton. Both locations are owned and operated by Sara Lacombe and her team.

Get a FREE B-12 Shot!

Boost your energy with a free B-12 shot! Simply enter your info below, then stop by our Clayton lounge at your convenience to redeem.

Name(Required)

Additional Offers

First-Time Special

Health & Wellness IV

for $79

(regularly $135)

Punch Pass

Buy 5 Health & Wellness IVs

Get 1 Free

(sharable with friends/family)

Year-Round

Buy 3

Get 1 Free

on select services

Not Sure Where to Start? Let Us Help.

Our nursing team will help you find the perfect wellness plan for YOUR goals. Choose the consultation level that’s right for you:

RN Consult

FREE

15 minutes

A quick Q&A to answer your questions and point you in the right direction.

Director of Nursing

$50

30 minutes

A deeper conversation to review your health history & build a personalized plan.

Medical Director

$100

45 minutes

A full evaluation with our physician, ideal for long-term wellness strategy.

Ready to Feel Your Best?

Book online or walk in today. We're here to help.

Select Your Location

Denver, CO
Littleton, CO
*Above Smokin Fins Restaurant
Elite IV Lounge : Breckenridge, CO

* Appointment Recommended

Jonesboro, AR
Paragould, AR
Clayton, NC
Goldsboro, NC
Clinton, MS