First Time? Come In For a FREE Consult
IV Therapy in Denver, CO
★★★★★ 405+ Google Reviews
Address
1562 S Pearl St
Denver, CO 80210
Phone
(720) 883-1665
Call or Text
Hours
Mon-Fri: 10am - 6pm
Saturday: 10am - 4pm
Sunday: 9am - 1pm
Welcome to Twin Rivers IV Denver
Located on historic South Pearl Street in Denver’s beloved Platt Park neighborhood, our Denver lounge offers a relaxing retreat for IV therapy, vitamin infusions, and wellness treatments. Whether you’re recovering from a big weekend, training for your next race, battling Denver’s dry climate, or simply looking to boost your energy, our experienced nursing team is here to help.
We opened our doors on South Pearl Street in 2019 as the second Twin Rivers location, following the success of our original Littleton lounge. Since then, we’ve become a neighborhood staple—just steps from the Sunday Farmers’ Market and surrounded by the tree-lined streets, boutique shops, and local restaurants that make Platt Park one of Denver’s most walkable neighborhoods.
We’re easily accessible from Washington Park, Baker, and the greater South Denver area. Street parking is available on Pearl Street, plus we have a private lot behind the building.
Can’t come to us? Our fully-equipped Airstream mobile lounge brings IV therapy directly to you anywhere in the Denver metro area.
Our Services in Denver
At Twin Rivers IV Denver, we offer a full range of IV therapy and wellness services administered by experienced registered nurses. Whether you’re seeking rapid hydration, immune support, athletic recovery, or anti-aging treatments, we’ll help you find the right solution for your wellness goals.
Our signature IV infusions deliver hydration, vitamins, and nutrients directly to your bloodstream for 100% absorption. Choose from our Health & Wellness IV, Immunity Boost, Athletic Recovery, Hangover Cure, and more. First-time special: $79 (regularly $135).
Quick vitamin shots for those on the go. B-12 for energy, Vitamin D for immunity, Glutathione for detox and skin health, and more. Same 100% absorption as IV therapy, but faster—perfect for busy schedules.
Nicotinamide Adenine Dinucleotide (NAD+) supports cellular energy production, DNA repair, and healthy aging. Available in multiple dosages via infusion or injection. Popular for mental clarity, anti-aging, and recovery support.
Targeted peptide treatments for weight management, muscle recovery, immune support, and anti-aging. Our medical team will help you determine the right protocol for your goals.
Comprehensive weight loss programs including Semaglutide and other medically-supervised treatments. Includes ongoing support, monitoring, and adjustments to help you reach your goals safely.
Comprehensive weight loss programs including Semaglutide and other medically-supervised treatments. Includes ongoing support, monitoring, and adjustments to help you reach your goals safely.
Enhance your IV therapy session with our infrared sauna—available exclusively at our Denver location. Infrared heat penetrates deep into tissues to promote detoxification, relaxation, pain relief, and improved circulation. Pair with any IV treatment for the ultimate wellness experience.
Can’t come to us? We’ll come to you! Our fully-equipped 1975 Airstream mobile lounge brings IV therapy anywhere in the Denver metro area. Perfect for individuals, groups of friends, bachelor/bachelorette parties, corporate wellness events, sporting events, and more. $100 service fee for groups under 6 (waived for larger groups).
Save approximately 50% on IV therapy with our monthly membership plans. Elite Membership ($150/mo): 2 Health & Wellness IVs + 2 B-12 injections. Elite+ Membership ($200/mo): 2 Health & Wellness IVs + 2 Boosts + 2 B-12 injections.
Meet Your Denver Team
Alyssa Kitting, RN, BSN
Lounge Manager
Alyssa pairs high-acuity Labor & Delivery experience with a wellness-first approach to IV infusion therapy. A DAISY Award–winning nurse with her BSN (cum laude), she’s Colorado-licensed and certified in BLS, ACLS, NRP, and C-EFM.
At Swedish Medical Center in Denver, Alyssa is known for establishing IV access quickly and comfortably while managing hydration and medication protocols with precision and a gentle, confident touch. Her background includes continuous bedside care for laboring, antepartum, postpartum, and surgical OB patients; real-time interpretation of maternal/fetal monitoring; and safe titration of high-alert medications.
Rooted in holistic, preventive wellness, Alyssa creates a supportive environment where clients feel seen, informed, and empowered. She brings the same standard of aseptic technique, patient advocacy, and clinical judgment to every IV—so you leave feeling better, cared for, and confident in your health journey.
Why Choose Twin Rivers Denver
Experienced RN Staff
Every IV is administered by a registered nurse with at least 5 years of clinical experience. No techs, no shortcuts.
Colorado-Born & Locally Owned
Founded in Colorado in 2018, Twin Rivers is a local business—not a franchise. Our founder still works in the lounges.
Relaxing Lounge Environment
Our Denver lounge is designed for comfort. Sink into a cozy chair, enjoy refreshments, and let us take care of you.
Mobile Services Available
Our vintage Airstream brings the lounge experience to you—at home, at work, or at your event anywhere in Denver.
Walk-Ins Welcome
No appointment needed for most services. Stop by when it's convenient for you.
Membership Savings
Members save approximately 50% on IV therapy. Plans start at $150/month.
What Our Denver Clients Say
★★★★★ 5.0 Rating
405+ Google Reviews
Visit Our Denver Lounge
Twin Rivers IV & Wellness Lounge
Address
1562 S Pearl St
Denver, CO 80210
Phone
(720) 883-1665
Call or Text
Hours
Mon-Fri: 10am - 6pm
Saturday: 10am - 4pm
Sunday: 9am - 1pm
Parking
Street parking on
S Pearl St. Private lot behind building (enter from alley).
Getting Here:
From I-25: Take the Broadway exit, head south on Broadway, turn left (east) on Louisiana Ave, then right (south) on S Pearl St. We’re located between Iowa and Arkansas Streets, in the heart of Platt Park.
Denver Location FAQs
Where is Twin Rivers IV located in Denver?
Do I need an appointment or can I walk in?
Do you offer mobile IV therapy in Denver?
Is IV therapy good for altitude sickness in Denver?
What can I expect at my first appointment?
Who administers the IVs?
Do you take insurance?
What are your Denver hours?
Monday through Friday 10am-6pm, Saturday 10am-4pm, and Sunday 9am-1pm. During Farmers’ Market season (May through November), we have special extended Sunday hours to accommodate the market crowd.
Get a FREE B-12 Shot!
Boost your energy with a free B-12 shot! Simply enter your info below, then stop by our Denver lounge at your convenience to redeem.
Not Sure Where to Start? Let Us Help.
Our nursing team will help you find the perfect wellness plan for YOUR goals.
Choose the consultation level that’s right for you:
RN Consult
FREE
A quick Q&A to answer your questions and point you in the right direction.
Director of Nursing
$50
A deeper conversation to review your health history & build a personalized plan.
Medical Director
$100
A full evaluation with our physician, ideal for long-term wellness strategy.
Ready to Feel Your Best?
Book online or walk in today. We're here to help.
Latest Blogs
How NAD+ Therapy Can Help Parents Reset This Back-to-School Season
As kids head back to school, parents everywhere kick into high gear. Between early mornings, endless errands, work deadlines, and after-school activities, it’s easy to feel like you’re running on
What Is IV Therapy? How It Works and How to Get the Most Out of It
IV therapy is one of the most talked-about wellness trends—and for good reason. Whether you’re recovering from a hangover, fighting fatigue, boosting your immune system, or looking for faster recovery
IV Hydration Therapy: 10 Reasons to Add It to Your Routine
As someone who spent years on the front lines in the ER, I saw firsthand how hydration, nutrition, and proactive care can make a meaningful difference—not just in emergencies, but
